a borítólapra  Súgó epa Copyright 
European chemical bulletinVol. 8., No.4. (2019.)

Tartalom

Classical and advanced chemical sciences

  • Vasiliy Georgievich Shtamburg ,
    Victor Vasilievich Shtamburg ,
    Andrey Alexandrovich Anishchenko ,
    Alexander Vladimirovich Mazepa ,
    Svetlana Valentinovna Shishkina ,
    Irina Sergeevna Konovalova :

    4-Nitrophenylglyoxal reacts with N-hydroxyurea both in water and in acetic acid forming the mixture of diastereomers of 3,4,5-trihydroxy-5-(4-nitrophenyl)imidazolidin-2-one. The diastereomer with cis-orientation of OH-groups dominates. In the acetic acid medium, 4-nitrophenylglyoxal reacts with 2-methylfuran selectively yielding 2-hydroxy-2-(5-methylfuran-2-yl)-1-(4-nitrophenyl)ethanone

    Keywords: 4-nitrophenylglyoxal;N-hydroxyurea; 2-methylfuran; 5-aryl-3,4,5-trihydroxyimidazolidin-2-ones; structure; α-benzoins

  • Santosh V. Deshmukh ,
    Chandrakant D. Pawar ,
    Dattatraya N. Pansare ,
    Sadhana L. Chavan ,
    Umakant D. Pawar ,
    Santosh L. Chavan ,
    Rajendra P. Pawar ,
    Milind B. Ubale :

    We synthesized substituted furansulfonamide compounds and developed reaction conditions for a series of 5-(substituted phenyl)-N-(2-oxo-2-(substituted phenyl)ethyl)-N-methylfuran-2-sulfonamide derivatives (4a-4m). We have optimized methodology for targets from milligram scale to multi gram scale. The structure of synthesized compounds were elucidated and confirmed by 1H NMR, 13C NMR, LCMS and purity was checked by HPLC. All the synthesized final compounds (4a-4m) are screened for antimicrobial activity (minimum inhibitory concentration) against a series of strains of Bacillus subtillis, Staphylococcus aureus and Escherichia coli for antibacterial activity and against the strains of Candida albicans, Aspergillus flavus and Aspergillus niger for antifungal activity. The results of antimicrobial screening data revealed most of compounds (4a-4m) showed moderate to promising microbial inhibitions.

    Keywords: furanes, sulfonamides, Suzuki, antimicrobial activity

  • Shritesh D. Jagtap ,
    Aniket P. Sarkate ,
    Arjun L. Khandare ,
    Ishudeep K. Narula ,
    Kshipra S. Karnik ,
    Dattatraya N. Pansare ,
    Rohini N. Shelke :

    A new method of thionyl chloride induced convenient synthesis of novel benzamides under solvent free conditions has been developed using benzoic acid and amines. The benzamides were synthesized through a coupling reaction of benzoic acid and different amines using thionyl chloride at room temperature. The abovementioned technique assists in the preparation of substituted benzamides which were obtained in good yields within 2-4 h using conventional heating. The developed method is flexible, economic, environment friendly; also is catalyst, ligand and solvent free and has major importance in industry and laboratory.

    Keywords: thionyl chloride;coupling reaction;benzamides;benzoic acid; solvent free.

  • S. V. Raut ,
    B. K. Dhotre ,
    S. P. More ,
    A. D. Tidke ,
    Pathan Mohd Arif :

    A clean and straightforward methodology developed for the synthesis of substituted indazoles using silica supported polyphosphoric acid (PPA-SiO2) catalyzed condensation reaction between substituted 2-hydroxybenzaldehydes or acetophenones and hydrazine hydrate or phenylhydrazine. The reaction conditions are optimized for different solvents at different temperatures. The yield of the products improved to 88 to 90 % using silica supported polyphosphoric acid as a catalyst, which is reusable, cost-effective and straightforward to synthesize.

    Keywords: silica supported polyphosphoric acid; hydrazine hydrate; phenyl hydrazine; o-hydroxyacetophenones; indazole

Materials and environmental chemistry

  • A. Rcheulishvili ,
    E. Ginturi ,
    L. Tugushi ,
    M. Gurielidze ,
    N. Rcheulishvili ,
    H.-Y. Holman :

    The process of assimilation of Cr(VI) and Cu by chromium-resistant bacteria (Arthrobacter globiformis 151B) and the influence of high-concentration Na ions on this process have been studied. The bacteria are known for their property to assimilate the hexavalent chromium ions from the environment intensively, to convert them into trivalent form and to accumulate it in the cell. Thanks to these properties, it is possible to use them for detoxification of the environment, polluted by highly toxic Cr(VI). The strain of bacteria under investigation was isolated from basalt samples taken from the places highly contaminated by Cr(VI) in Kazreti. The solutions of the studied elements (Cr and Cu) and Na were introduced simultaneously into the nutrient medium. We studied the influence of different concentrations of Na ions during a different period of time of bacteria cultivation (17h, 24 h, 48 h, 96 h and 144 hours) on the process of assimilation of Cr and Cu by bacteria. The concentration of Na in the nutrient medium was 2, 3.5, 6.5 and 9.5 g mL-1. For determination of the content of metals (Cr, Cu, and Na) in the cell, after the cultivation of bacteria, the precipitation of cells by centrifuge and the preparation of the obtained bacterial pellet for the analysis were carried out. The content of metals was measured by atom-absorption spectrometry.

    Keywords: bacteria; Arthrobacter globiformis 151B; biomass; metals; concentration

Industrial and engineering chemistry, biotechnology

  • Fayza S. Hashem ,
    Mustafa K. Metwally ,
    Sherif Mostafa ,
    Alaa I. Mohamed :

    The chlorine industry sludge (CLS), which is a solid by-product resulted from the chlorine industry plants, is successfully applied as an effective adsorbent for removal of the heavy metal ions. CLS was activated by grinding to about 10 μm particle size and burned to 700 oC for 3 h (ACLS) The physicochemical characteristics of CLS and ACLS were investigated using X-ray diffraction (XRD), scanning electron microscope (SEM) coupled with energy dispersed X-ray analysis (EDX) unit and texture propertied using N2 adsorption-desorption isotherms. CLS and ACLS are tested for removal of Cu(II), Cd(II) and Pb(II) from the wastewater solutions under various factors such as contact time, pH and adsorbent dose. Results showed that CLS as well as ACLS exhibit high removal efficiency of the studied heavy metal ions. These nominate them as low-cost adsorbent for Cu(II), Cd(II), and Pb(II) ions.

    Keywords: Chlorine industry sludge; heavy metals; wastewater treatment; activated brine sludge; non-activated brine sludge